Memo 8: Monkeypox
Key Points
DHS came out with a Monkeypox Report: https://www.dhs.gov/sites/default/files/2022-07/22_0712_st_monkeypox_mql.pdf
“Data demonstrating effectiveness against MPXV are not available for most common disinfectants, however testing with vaccinia virus (a close relative) suggests that bleach, Virkon, Dettol, and Sanytex, are effective.”
“U.S. Environmental Protection Agency recommends the use of bleach and a number of quaternary ammonium reagents for use against emerging viral pathogens.”
Patients are contagious during the first week of the rash and direct contact should be prevented until lesions have crusted.
“Humans can be contagious before a visible rash appears and can continue shedding the virus weeks after symptoms have dissipated.”
Monkeypox can live on surfaces for weeks, but this is not related to its transmissibility from these surfaces.
US has the most cases of monkeypox and a higher rate of increase
Thursday, 2pm briefing with CDC’s Becerra to decide whether or not Biden admin will declare Monkeypox a public health emergency. This will mean the US has access to funds to increase accessibility and services for the people.
Public Health Emergency Declaration: https://www.phe.gov/Preparedness/legal/Pages/phedeclaration.aspx
Fact sheet listing U.S. Department of Health and Human Services Response to the Monkeypox Outbreak: https://www.hhs.gov/about/news/2022/07/21/fact-sheet-us-department-of-health-and-human-services-response-to-the-monkeypox-outbreak.html
In depth presentation on treatment and testing for monkeypox: https://emergency.cdc.gov/coca/ppt/2022/072622_slides.pdf
Considerations for PEP
“CDC recommends that the vaccine series be initiated within 4 days from the date of exposure for the best chance to prevent onset of the disease”
“If initiated between 4 and 14 days after the date of exposure, vaccination may reduce the symptoms of disease, but may not prevent the disease”
CA, NY & Illinois declares State of Emergency for monkeypox
Communications toolkit: https://www.cdph.ca.gov/Programs/OPA/Pages/Communications-Toolkits/Monkeypox.aspx
California:
Access to the antiviral prescription drug tecovirimat (TPOXX) used to treat monkeypox is limited, but the treatment can now be administered at more than 30 facilities and providers across the state.
The world’s only monkeypox vaccine manufactor, Bavarian Nordic, is halting production until October 2022
Only 2.5 million more vaccines for US
World needs around 10 million doses
European plant was planned to be stopped before the public health emergency declaration to create new production lines for vaccines against rabies and tick-borne encephalitis
Activists storm stage at International AIDS Conference to demand global action
Demands: https://www.prep4all.org/monkeypox
Changing the name of monkeypox “isn’t a priority” according to Keletoso Makofane, a public health researcher and activist who is a fellow at the FXB Center for Health and Human Rights at Harvard.
Sources
https://www.cdc.gov/poxvirus/monkeypox/lab-personnel/lab-procedures.html
https://healthpolicy-watch.news/category/infectious-disease/monkeypox/
https://healthpolicy-watch.news/exclusive-china-monkeypox-bavarian-nordics/
https://www.dhs.gov/sites/default/files/2022-07/22_0712_st_monkeypox_mql.pdf
https://www.cidrap.umn.edu/news-perspective/2022/08/who-us-has-biggest-jump-monkeypox-cases
https://www.phe.gov/Preparedness/legal/Pages/phedeclaration.aspx
https://www.gov.ca.gov/wp-content/uploads/2022/08/8.1.22-Monkeypox-SOE-signed.pdf?emrc=2a3e09